Mitochondrial DNA Mutation Detection by Electrospray Mass Spectrometry
نویسندگان
چکیده
منابع مشابه
Mitochondrial DNA mutation detection by electrospray mass spectrometry.
BACKGROUND Mitochondrial DNA (mtDNA) mutations cause a large spectrum of clinically important neurodegenerative, neuromuscular, cardiovascular, and endocrine disorders. We describe the novel application of electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (ESI-FTICR MS) to the rapid and accurate identification of pathogenic mtDNA variants. METHODS In a blinde...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2007
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2006.074823